Anomalous mixing behaviour in rotationally actuated microfluidic devices.

نویسندگان

  • Debapriya Chakraborty
  • Marc Madou
  • Suman Chakraborty
چکیده

We analyse the characteristics of two-fluid mixing in T-shaped microchannels on rotating platforms (Lab-on-a-Compact-Disk framework). Three regimes of mixing were identified based on the distinct flow behaviour in each of these regimes. A diffusion-based mixing regime was obtained for low rotation speeds. A Coriolis force based mixing regime was observed for intermediate rotation speeds, which introduced some nontrivial aspects in the mixing behaviour, which was explained through scaling analysis. At very high rotational speeds, rapid mixing close to the junction was achieved by exploiting flow instabilities (instability based mixing). A good agreement between the theoretical calculations and the experimental observations was obtained.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A novel vortex mixer actuated by one-shot electricity-free pumps

Effective mixing is vitally important to many microfluidic devices in the areas of biotechnical industries, analytic chemistry and medical industries. However, most micro-mixers require complicated fabrication procedures, possibly inappropriate for practical microfluidic utilization. These mixers generally operate under low Reynolds-number conditions, causing a relatively long reaction time in ...

متن کامل

Active Continuous-Flow Micromixer Using an External Braille Pin Actuator Array

We present a continuous-flow active micromixer based on channel-wall deflection in a polydimethylsiloxane (PDMS) chip for volume flows in the range up to 2 μL s −1 which is intended as a novel unit operation for the microfluidic Braille pin actuated platform. The chip design comprises a main microchannel connected to a series of side channels with dead ends aligned on the Braille pins. Computer...

متن کامل

Transport of live yeast and zebrafish embryo on a droplet digital microfluidic platform.

We demonstrate the first programmed transport of live yeast (Saccharomyces cerevisiae) and a zebrafish embryo (Danio rerio) within droplets in a two-plate digital microfluidic device. The yeast remained viable after transport, and the actuated droplets left no yeast behind. A zebrafish embryo transported 2 hours after fertilization developed normally and hatched. Dechorionation was demonstrated...

متن کامل

A Rapid Micromixer for Centrifugal Microfluidic Platforms

This paper presents an innovative mixing technology for centrifugal microfluidic platforms actuated using a specially designed flyball governor. The multilayer microfluidic disc was fabricated using a polydimethylsiloxane (PDMS) replica molding process with a soft lithography technique. The operational principle is based on the interaction between the elastic covering membrane and an actuator p...

متن کامل

Ultrasensitive microfluidic solid-phase ELISA using an actuatable microwell-patterned PDMS chip.

Quantitative detection of low abundance proteins is of significant interest for biological and clinical applications. Here we report an integrated microfluidic solid-phase ELISA platform for rapid and ultrasensitive detection of proteins with a wide dynamic range. Compared to the existing microfluidic devices that perform affinity capture and enzyme-based optical detection in a constant channel...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Lab on a chip

دوره 11 17  شماره 

صفحات  -

تاریخ انتشار 2011